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Article

The FADS1 genotypes modify the effect of linoleic acid-enriched diet on adipose tissue inflammation via pro-inflammatory eicosanoid metabolism.

European journal of nutrition - 1 Oct 2022

Vaittinen Maija, Lankinen Maria A, Käkelä Pirjo, Ågren Jyrki, Wheelock Craig E, Laakso Markku, Schwab Ursula, Pihlajamäki Jussi

Abstract excerpt

PURPOSE: Fatty acid desaturase (FADS) variants associate with fatty acid (FA) and adipose tissue (AT) metabolism and inflammation. Thus, the role of FADS1 variants in the regulation of dietary linoleic acid (LA)-induced effects on AT inflammation was investigated. METHODS: Subjects homozygotes for the TT and CC genotypes of the FADS1-rs174550 (TT, n = 25 and CC, n = 28) or -rs174547 (TT, n = 42 and CC, n = 28),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35701670
DOI: 10.1007/s00394-022-02922-y
PMCID: PMC9464166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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