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Article

Modification in mitochondrial function is associated with the FADS1 variant and its interaction with alpha-linolenic acid-enriched diet-An exploratory study.

Journal of lipid research - 1 Oct 2024

Vaittinen Maija, Ilha Mariana, Sehgal Ratika, Lankinen Maria A, Ågren Jyrki, Käkelä Pirjo, Virtanen Kirsi A, Laakso Markku, Schwab Ursula, Pihlajamäki Jussi

Abstract excerpt

Fatty acid desaturase (FADS1) variant-rs174550 strongly regulates polyunsaturated fatty acid (PUFA) biosynthesis. Additionally, the FADS1 is related to mitochondrial function. Thus, we investigated whether changes in mitochondrial function are associated with the genetic variation in FADS1 (rs174550) in human adipocytes isolated from individuals consuming diets enriched with either dietary alpha-linolenic (ALA)...

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Source

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Identifiers

PMID: 39218219
DOI: 10.1016/j.jlr.2024.100638
PMCID: PMC11459653

Genes

FADS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Modification in mitochondrial function is associated with the FADS1 variant and its interaction with alpha-linolenic acid-enriched diet-An exploratory study.PMID 39218219Read ↗

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