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Article

SLCO1B1 Variants and Angiotensin Converting Enzyme Inhibitor (Enalapril)-Induced Cough: a Pharmacogenetic Study.

Scientific reports - 26 Nov 2015

Luo Jian-Quan, He Fa-Zhong, Wang Zhen-Min, Sun Ning-Ling, Wang Lu-Yan, Tang Gen-Fu, Liu Mou-Ze, Li Qing, Chen Xiao-Ping, Liu Zhao-Qian, Zhou Hong-Hao, Zhang Wei

Abstract excerpt

Clinical observations suggest that incidence of cough in Chinese taking angiotensin converting enzyme inhibitors is much higher than other racial groups. Cough is the most common adverse reaction of enalapril. We investigate whether SLCO1B1 genetic polymorphisms, previously reported to be important determinants of inter-individual variability in enalapril pharmacokinetics, are associated with the...

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Identifiers

PMID: 26607661
DOI: 10.1038/srep17253
PMCID: PMC4660479

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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