Article
A randomized trial of genotype-guided perindopril use.
Journal of hypertension - 1 Nov 2023
Lee Sang-Hak, Lee Chan Joo, Kang Yura, Park Jung Mi, Lee Ji Hyun
Abstract excerpt
OBJECTIVE: Cough caused by angiotensin-converting enzyme inhibitors (ACEIs) limits their clinical application and cardiovascular benefits. This randomized trial investigated whether genotype-guided perindopril use could reduce drug-related cough in 20 to 79-year-old individuals with hypertension. METHODS: After screening 120 patients and randomization, 68 were assigned to genotyping ( n = 41) and control ( n...
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