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Article

Pharmacogenetic predictors of development of secondary to enalapril dry cough in hypertensive patients.

Drug metabolism and personalized therapy - 1 Sept 2023

Sychev Ivan V, Denisenko Natalia P, Kachanova Anastasiya A, Lapshtaeva Anna V, Goncharova Ludmila N, Mirzaev Karin B, Sychev Dmitry A

Abstract excerpt

OBJECTIVES: Development of the secondary to ACEI cough leads to discontinuation of the drugs of this group. Assessing the safety of the ACEIs with further development of customized approaches for their administration is a major scientific and practical problem. The objective of this study was to assess the association of the genetic markers with the development of the adverse drug reaction in the form of...

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PMID: 37201212
DOI: 10.1515/dmpt-2023-0008

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