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Article

Genetic Variants Associated with Adverse Events after Angiotensin-Converting Enzyme Inhibitor Use: Replication after GWAS-Based Discovery.

Yonsei medical journal - 1 Apr 2022

Lee Chan Joo, Choi Bogeum, Pak Hayeon, Park Jung Mi, Lee Ji Hyun, Lee Sang-Hak

Abstract excerpt

PURPOSE: Angiotensin-converting enzyme inhibitors (ACEIs) are medications generally prescribed for patients with high cardiovascular risk; however, they are suboptimally used due to frequent adverse events (AEs). The present study aimed to identify and replicate the genetic variants associated with ACEI-related AEs in the Korean population. MATERIALS AND METHODS: A two-stage approach employing genome-wide...

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Identifiers

PMID: 35352885
DOI: 10.3349/ymj.2022.63.4.342
PMCID: PMC8965428

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