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Genome-wide association study of ACE inhibitor-induced cough implicates neuropeptides and shows genetic overlap with chronic dry cough

2022-06-30

Abstract excerpt

<h4>Summary</h4> ACE inhibitors (ACEIs) are commonly prescribed for hypertension, a global risk factor for cardiovascular disease. Their primary side effect is a dry cough which affects 5-35% of users. As clinical guidelines recommend switching those experiencing cough to an angiotensin-II receptor blocker, we have used this switch as a proxy for ACEI-induced cough. Through a two-stage multi-ancestry genome-wide a...

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Identifiers and source

Literature Corpus work
7824bc09-8cce-5f76-9f9e-cd4d7f78ead8
DOI
10.1101/2022.06.30.22277097
Open publication

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Genome-wide association study of ACE inhibitor-induced cough implicates neuropeptides and shows genetic overlap with chronic dry coughDOI 10.1101/2022.06.30.22277097
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