Article
Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough.
Pharmacogenetics and genomics - 1 Jan 2011
Grilo Antonio, Sáez-Rosas María P, Santos-Morano Juan, Sánchez Elena, Moreno-Rey Concha, Real Luis M, Ramírez-Lorca Reposo, Sáez María E
Abstract excerpt
BACKGROUND AND OBJECTIVE: Angiotensin-converting enzyme inhibitors (ACEi) are the first selected drugs for hypertensive patients because of its protective properties against heart and kidney diseases. Persistent cough is a common adverse reaction associated with ACEi, which can bind to the treatment cessation, but its etiology remains an unresolved issue. The most accepted mechanism is that the inhibition of ACEi...
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