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Article

A Bayesian model for detection of high-order interactions among genetic variants in genome-wide association studies.

BMC genomics - 25 Nov 2015

Wang Juexin, Joshi Trupti, Valliyodan Babu, Shi Haiying, Liang Yanchun, Nguyen Henry T, Zhang Jing, Xu Dong

Abstract excerpt

BACKGROUND: A central question for disease studies and crop improvements is how genetics variants drive phenotypes. Genome Wide Association Study (GWAS) provides a powerful tool for characterizing the genotype-phenotype relationships in complex traits and diseases. Epistasis (gene-gene interaction), including high-order interaction among more than two genes, often plays important roles in complex traits and...

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Identifiers

PMID: 26607428
DOI: 10.1186/s12864-015-2217-6
PMCID: PMC4660815

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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