Article
Statistical analysis of genetic interactions.
Genetics research - 1 Dec 2010
Yi Nengjun
Abstract excerpt
Many common human diseases and complex traits are highly heritable and influenced by multiple genetic and environmental factors. Although genome-wide association studies (GWAS) have successfully identified many disease-associated variants, these genetic variants explain only a small proportion of the heritability of most complex diseases. Genetic interactions (gene-gene and gene-environment) substantially...
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