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Article

Higher-order genetic interaction discovery with network-based biological priors.

Bioinformatics (Oxford, England) - 30 Jun 2023

Pellizzoni Paolo, Muzio Giulia, Borgwardt Karsten

Abstract excerpt

MOTIVATION: Complex phenotypes, such as many common diseases and morphological traits, are controlled by multiple genetic factors, namely genetic mutations and genes, and are influenced by environmental conditions. Deciphering the genetics underlying such traits requires a systemic approach, where many different genetic factors and their interactions are considered simultaneously. Many association mapping...

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PMID: 37387173
DOI: 10.1093/bioinformatics/btad273
PMCID: PMC10311320

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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