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Article

Clinical and Steroidogenic Characteristics of Aldosterone-Producing Adenomas With ATPase or CACNA1D Gene Mutations.

The Journal of clinical endocrinology and metabolism - 1 Feb 2016

Kitamoto Takumi, Suematsu Sachiko, Yamazaki Yuto, Nakamura Yasuhiro, Sasano Hironobu, Matsuzawa Yoko, Saito Jun, Omura Masao, Nishikawa Tetsuo

Abstract excerpt

OBJECT: This comparative study clarified the clinical characteristics and in vitro steroidogenic activities of aldosterone-producing adenomas (APAs) harboring ATPase or CACNA1D gene mutations. DESIGN AND PATIENTS: Genetic testing was performed on 159 unilateral APAs. Somatic ATPase and CACNA1D gene mutations were analyzed in 42 APA tissues without KCNJ5 gene mutations. RESULTS: ATP1A1, ATP2B3, and CACNA1D...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26606680
DOI: 10.1210/jc.2015-3284

Genes

KCNJ5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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