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Article

Aldosterone-Regulating Receptors and Aldosterone-Driver Somatic Mutations.

Frontiers in endocrinology - 1 Jan 2021

Lim Jung Soo, Plaska Samuel W, Rege Juilee, Rainey William E, Turcu Adina F

Abstract excerpt

Background: Somatic gene mutations that facilitate inappropriate intracellular calcium entrance have been identified in most aldosterone-producing adenomas (APAs). Studies suggest that angiotensin II and adrenocorticotropic hormone (ACTH) augment aldosterone production from APAs. Little is known, however, regarding possible variations in response to hormonal stimuli between APAs with different aldosterone-driver...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to G Protein-Coupled Inwardly-Rectifying Potassium Channels

Share to Receptor, Angiotensin, Type 1

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Source

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Identifiers

PMID: 33796077
DOI: 10.3389/fendo.2021.644382
PMCID: PMC8008747

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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