Article
Histopathology and Genetic Causes of Primary Aldosteronism in Young Adults.
The Journal of clinical endocrinology and metabolism - 18 Aug 2022
Nanba Kazutaka, Baker Jessica E, Blinder Amy R, Bick Nolan R, Liu Chia-Jen, Lim Jung Soo, Wachtel Heather, Cohen Debbie L, Williams Tracy Ann, Reincke Martin, Lyden Melanie L, Bancos Irina, Young William F, Else Tobias, Giordano Thomas J, Udager Aaron M, Rainey William E
Abstract excerpt
CONTEXT: Due to its rare incidence, molecular features of primary aldosteronism (PA) in young adults are largely unknown. Recently developed targeted mutational analysis identified aldosterone-driver somatic mutations in aldosterone-producing lesions, including aldosterone-producing adenomas (APAs), aldosterone-producing nodules (APNs), and aldosterone-producing micronodules, formerly known as...
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