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Article

Histological Characterization of Aldosterone-producing Adrenocortical Adenomas with Different Somatic Mutations.

The Journal of clinical endocrinology and metabolism - 1 Mar 2020

Ono Yoshikiyo, Yamazaki Yuto, Omata Kei, Else Tobias, Tomlins Scott A, Rhayem Yara, Williams Tracy Ann, Reincke Martin, Carling Tobias, Monticone Silvia, Mulatero Paolo, Beuschlein Felix, Ito Sadayoshi, Satoh Fumitoshi, Rainey William E, Sasano Hironobu

Abstract excerpt

CONTEXT: Aldosterone-producing adrenocortical adenomas (APAs) are mainly composed of clear (lipid rich) and compact (eosinophilic) tumor cells. The detailed association between these histological features and somatic mutations (KCNJ5, ATP1A1, ATP2B3, and CACNA1D) in APAs is unknown. OBJECTIVE: To examine the association between histological features and individual genotypes in APAs. METHODS: Examination of 39...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31789380
DOI: 10.1210/clinem/dgz235
PMCID: PMC7048684

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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