Article
Mitochondrial DNA polymorphisms and the risk of Parkinson's disease in Taiwan.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2007
Chen C M, Kuan C C, Lee-Chen G-J, Wu Y R
Abstract excerpt
A critical role of mitochondrial dysfunction has been implicated in the pathogenesis of Parkinson's disease (PD). The association of mitochondrial DNA (mtDNA) polymorphisms 9055G/A, 10398G/A and 13708G/A with PD has been controversial. In this study we analyzed whether these three genetic polymorphisms are associated with PD in a cohort of 416 PD cases and 372 ethnically matched controls. The allele frequency...
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