Article
Mitochondrial DNA polymorphisms and risk of Parkinson's disease in Spanish population.
Journal of the neurological sciences - 15 Sept 2005
Huerta Cecilia, Castro Mónica G, Coto Eliecer, Blázquez Marta, Ribacoba René, Guisasola Luis M, Salvador Carlos, Martínez Carmen, Lahoz Carlos H, Alvarez Victoria
Abstract excerpt
Mutations in mitochondrial DNA (mtDNA) have been implicated in the development of Parkinson's disease (PD). Mitochondrial function is necessary to supply the energy required for cell metabolism, and mutations in mitochondrial genes should have a deleterious effect in neuronal function. An association between several common mtDNA-polymorphisms and the risk of PD has been described. To test this association among...
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