Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of promoter of the tuberculosis-resistant gene intracellular pathogen resistance 1.

Immunologic research - 1 Feb 2016

Wu Yongyan, Liu Fayang, Zhang Yan, Wang Yongsheng, Guo Zekun, Zhang Yong

Abstract excerpt

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, which most commonly affects the lungs and causes over 1.3 million people die annually. Variation in host genes is known to influence susceptibility to tuberculosis. Expression of the intracellular pathogen resistance 1 (Ipr1) gene could enhance the host resistance to mycobacterium. Here, we analyzed the coding region sequence and promoter...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunity, Innate
Share to Interferon-gamma
Share to Macrophages

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred BALB C

Share to Mycobacterium tuberculosis

Share to STAT1 Transcription Factor

Share to Transcriptional Activation

Share to Tuberculosis, Pulmonary

Source

Identifiers

PMID: 26590945
DOI: 10.1007/s12026-015-8732-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of promoter of the tuberculosis-resistant gene intracellular pathogen resistance 1.PMID 26590945Read ↗

Ipr1 gene mediates innate immunity to tuberculosis.Semantic proximity Read ↗

Genetic dissection of host resistance to Mycobacterium tuberculosis: the sst1 locus and the Ipr1 gene.Semantic proximity Read ↗

Interleukin-1 receptor antagonist is a conserved early factor for exacerbating tuberculosis susceptibilitySemantic proximity Read ↗

SP110b Controls Host Immunity and Susceptibility to Tuberculosis.Semantic proximity Read ↗

Infection genomics: Nramp1 as a major determinant of natural resistance to intracellular infections.Semantic proximity Read ↗

Differential expression of an alternative splice variant of IL-12Rβ1 impacts early dissemination in the mouse and associates with disease outcome in both mouse and humans exposed to tuberculosisSemantic proximity Read ↗

Type I IFN signaling in the absence of IRGM1 promotes <i>M. tuberculosis</i> replication in immune cells by suppressing T cell responsesSemantic proximity Read ↗

A proline deletion in IFNAR1 impairs IFN-signaling and underlies increased resistance to tuberculosis in humans.Semantic proximity Read ↗

Type I IFN signaling in the absence of IRGM1 promotes M. tuberculosis replication in immune cells by suppressing T cell responsesSemantic proximity Read ↗

Genetic control of resistance to experimental infection with virulent Mycobacterium tuberculosis.Semantic proximity Read ↗

Advances on the Role and Applications of Interleukin-1 in Tuberculosis.Semantic proximity Read ↗

IRGM gene polymorphisms and haplotypes associate with susceptibility of pulmonary tuberculosis in Chinese Hubei Han population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.