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Article

IRGM gene polymorphisms and haplotypes associate with susceptibility of pulmonary tuberculosis in Chinese Hubei Han population.

Tuberculosis (Edinburgh, Scotland) - 1 Jan 2016

Yuan Leyong, Ke Zunqiong, Ma Jun, Guo Yi, Li Yan

Abstract excerpt

Human immunity-related GTPase M (IRGM) is found to play an important role in defense against intracellular pathogen Mycobacterium tuberculosis (M. tuberculosis) in vitro by regulating autophagy. The objective of the study was to determine the association between IRGM polymorphisms and susceptibility to pulmonary tuberculosis (PTB) in Chinese Hubei Han population. In this study, 237 PTB patients and 269 healthy...

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Identifiers

PMID: 26786655
DOI: 10.1016/j.tube.2015.10.014

Genes

IRGM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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