Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pathobiochemical signatures of cholestatic liver disease in bile duct ligated mice

20 Nov 2015

Abstract excerpt

BACKGROUND: Disrupted bile secretion leads to liver damage characterized by inflammation, fibrosis, eventually cirrhosis, and hepatocellular cancer. As obstructive cholestasis often progresses insidiously, markers for the diagnosis and staging of the disease are urgently needed. To this end, we compiled a comprehensive data set of serum markers, histological parameters and transcript profiles at 8 time points of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Connective Tissue Growth Factor Research
Share to Liver Diseases and Immunity
Share to Liver physiology and pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26589287
DOI: 10.1186/s12918-015-0229-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pathobiochemical signatures of cholestatic liver disease in bile duct ligated micePMID 26589287Read ↗

Transcriptomic signatures of progressive and regressive liver fibrosis and portal hypertensionSemantic proximity Read ↗

Transcriptomic signatures of progressive and regressive liver fibrosis and portal hypertensionSemantic proximity Read ↗

Molecular characterization of chronic liver disease dynamics: From liver fibrosis to acute-on-chronic liver failureSemantic proximity Read ↗

Multitranscriptome analyses reveal prioritized genes specifically associated with liver fibrosis progression independent of etiologySemantic proximity Read ↗

Spatial single-cell interactome and niche-specific molecular signatures in alcohol-related liver diseaseSemantic proximity Read ↗

A Fibrosis‐Independent Hepatic Transcriptomic Signature Identifies Drivers of Disease Progression in Primary Sclerosing CholangitisSemantic proximity Read ↗

Spatio-Temporal Multiscale Analysis of Western Diet-Fed Mice Reveals a Translationally Relevant Sequence of Events during NAFLD ProgressionSemantic proximity Read ↗

An Integrated Single-Cell Atlas Reveals Hepatic Stellate Cell Heterogeneity and Spatiotemporal Dynamics after Liver InjurySemantic proximity Read ↗

Integrative single-cell and spatial transcriptomic analyses identify a pathogenic cholangiocyte niche and TNFRSF12A as therapeutic target for biliary atresiaSemantic proximity Read ↗

Rationale and targets for antifibrotic therapies.Semantic proximity Read ↗

Tgfb3 and Mmp13 regulated the initiation of liver fibrosis progression as dynamic network biomarkersSemantic proximity Read ↗

Single‐cell and spatial transcriptomics reveal the fibrosis‐related immune landscape of biliary atresiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.