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Article

Tgfb3 and Mmp13 regulated the initiation of liver fibrosis progression as dynamic network biomarkers

2 Dec 2020

Abstract excerpt

Liver fibrogenesis is a complex scar-forming process in the liver. We suggested that the liver first responded to chronic injuries with gradual changes, then reached the critical state and ultimately resulted in cirrhosis rapidly. This study aimed to identify the tipping point and key molecules driving liver fibrosis progression. Mice model of liver fibrosis was induced by thioacetamide (TAA), and liver tissues...

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PMID: 33269546
DOI: 10.1111/jcmm.16140

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