Article
Molecular characterization of chronic liver disease dynamics: From liver fibrosis to acute-on-chronic liver failure
4 Apr 2022
Abstract excerpt
Background & Aims: The molecular mechanisms driving the progression from early-chronic liver disease (CLD) to cirrhosis and, finally, acute-on-chronic liver failure (ACLF) are largely unknown. Our aim was to develop a protein network-based approach to investigate molecular pathways driving progression from early-CLD to ACLF. Methods: Transcriptome analysis was performed on liver biopsies from patients at...
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