Article
Rationale and targets for antifibrotic therapies.
Gastroenterologie clinique et biologique - 1 Jan 2000
Schuppan D, Popov Y
Abstract excerpt
We have made striking progress in our understanding of the biochemistry and cell biology that underlies liver fibrosis and cirrhosis, including the development of strategies and agents to prevent and reverse fibrosis and incipient cirrhosis. However, translation of this knowledge into clinical practice has been hampered by the limitation of many in vitro and in vivo models to confirm mechanisms and to test...
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