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Article

The lncRNA RZE1 Controls Cryptococcal Morphological Transition

20 Nov 2015

Abstract excerpt

In the fungal pathogen Cryptococcus neoformans, the switch from yeast to hypha is an important morphological process preceding the meiotic events during sexual development. Morphotype is also known to be associated with cryptococcal virulence potential. Previous studies identified the regulator Znf2 as a key decision maker for hypha formation and as an anti-virulence factor. By a forward genetic screen, we...

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PMID: 26588844
DOI: 10.1371/journal.pgen.1005692

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