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Article

Induction of the<i>Candida albicans</i>Filamentous Growth Program by Relief of Transcriptional Repression: A Genome-wide Analysis

7 Apr 2005

Abstract excerpt

Candida albicans, the major human fungal pathogen, undergoes a reversible morphological transition from blastospores (round budding cells) to filaments (elongated cells attached end-to-end). This transition, which is induced upon exposure of C. albicans cells to a number of host conditions, including serum and body temperature (37 degrees C), is required for virulence. Using whole-genome DNA microarray analysis,...

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PMID: 15814840
DOI: 10.1091/mbc.e05-01-0073

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