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Epistatic genetic interactions govern morphogenesis during sexual reproduction and infection in a global human fungal pathogen

2021-12-09

Abstract excerpt

Cellular development is orchestrated by evolutionarily conserved signaling pathways, which are often pleiotropic and involve intra- and inter-pathway epistatic interactions that form intricate, complex regulatory networks. Cryptococcus species are a group of closely-related human fungal pathogens that grow as yeasts yet transition to hyphae during sexual reproduction. Additionally, during infection they can form...

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Literature Corpus work
69b6eb08-761f-5f1a-93bd-2922c6220207
DOI
10.1101/2021.12.09.472005
Open publication

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Epistatic genetic interactions govern morphogenesis during sexual reproduction and infection in a global human fungal pathogenDOI 10.1101/2021.12.09.472005
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