Article
RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans.
Cell communication and signaling : CCS - 3 Jan 2020
Xu Huihui, Fang Tianshu, Omran Raha Parvizi, Whiteway Malcolm, Jiang Linghuo
Abstract excerpt
BACKGROUND: The calcium/calcineurin signaling pathway is mediated by the transcription factors NFAT (nuclear factor of activated T cells) in mammals and Crz1 (calcineurin-responsive zinc finger 1) in yeasts and other lower eukaryotes. A previous microarray analysis identified a putative Crz1-binding motif in promoters of its target genes in Candida albicans, but it has not been experimentally demonstrated....
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