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<i>Aspergillus fumigatus</i> transcription factor ZfpA regulates hyphal development and alters susceptibility to antifungals and neutrophil killing during infection

2023-01-26

Abstract excerpt

Hyphal growth is essential for host colonization during Aspergillus infection. The transcription factor ZfpA regulates A. fumigatus hyphal development including branching, septation, and cell wall composition. However, how ZfpA affects fungal growth and susceptibility to host immunity during infection has not been investigated. Here, we use the larval zebrafish- Aspergillus infection model and primary human neu...

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Literature Corpus work
a5eec14a-20e0-5eca-b9b6-9d4016003398
DOI
10.1101/2023.01.25.525624
Open publication

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