Article
The anatomical distribution of genetic associations.
Nucleic acids research - 15 Dec 2015
Wells Alan, Kopp Nathan, Xu Xiaoxiao, O'Brien David R, Yang Wei, Nehorai Arye, Adair-Kirk Tracy L, Kopan Raphael, Dougherty J D
Abstract excerpt
Deeper understanding of the anatomical intermediaries for disease and other complex genetic traits is essential to understanding mechanisms and developing new interventions. Existing ontology tools provide functional, curated annotations for many genes and can be used to develop mechanistic hypotheses; yet information about the spatial expression of genes may be equally useful in interpreting results and forming...
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