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Article

The gene expression landscape of disease genes.

Genome biology - 9 Feb 2026

García-González Judit, Cote Alanna C, Garcia-Gonzalez Saul, Liou Lathan, O'Reilly Paul F

Abstract excerpt

BACKGROUND: Fine-mapping and gene-prioritisation techniques applied to the latest genome-wide association study (GWAS) results have prioritised hundreds of genes as causally associated with disease. Here we leverage these recently compiled lists of high-confidence causal genes to interrogate where in the body disease genes operate, providing a more direct approach than previous studies, which have primarily...

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Gene Expression Profiling
Gene Expression Regulation
Genetic Predisposition to Disease
Genome-Wide Association Study
Neoplasms

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PMID: 41664080
DOI: 10.1186/s13059-026-03958-7
PMCID: PMC12983648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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