Article
Ten common genetic variants associated with colorectal cancer risk are not associated with survival after diagnosis.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jul 2010
Tenesa Albert, Theodoratou Evropi, Din Farhat V N, Farrington Susan M, Cetnarskyj Roseanne, Barnetson Rebecca A, Porteous Mary E, Campbell Harry, Dunlop Malcolm G
Abstract excerpt
PURPOSE: To date, genomewide association studies have identified 10 genetic loci associated with colorectal cancer (CRC) susceptibility. We hypothesized that these loci might also affect cancer survival. EXPERIMENTAL DESIGN: To determine whether single-nucleotide polymorphisms tagging these 10 loci influenced all-cause and CRC-specific mortality, we prospectively followed survival outcomes for 2,838 Scottish...
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