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Article

An SNP Marker Predicts Colorectal Cancer Outcomes with 5-Fluorouracil-Based Adjuvant Chemotherapy Post-Resection.

International journal of molecular sciences - 17 Jun 2024

Chien Hao, Chu Yu-De, Hsu Yi-Ping, Yeh Chau-Ting, Lai Ming-Wei, Chang Ming-Ling, Lim Siew-Na, Chen Chun-Wei, Lin Wey-Ran

Abstract excerpt

Colorectal cancer (CRC) is a global health concern, necessitating adjuvant chemotherapy post-curative surgery to mitigate recurrence and enhance survival, particularly in intermediate-stage patients. However, existing therapeutic disparities highlight the need for biomarker-guided adjuvant chemotherapy to achieve better CRC inhibition. This study explores the molecular mechanisms underlying the inhibition of CRC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38928347
DOI: 10.3390/ijms25126642
PMCID: PMC11203489

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