Article
Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome.
PloS one - 1 Jan 2012
Hoskins Janelle M, Ong Pei-Shi, Keku Temitope O, Galanko Joseph A, Martin Christopher F, Coleman Clint A, Wolfe Michelle, Sandler Robert S, McLeod Howard L
Abstract excerpt
BACKGROUND: Low-penetrance genetic variants have been increasingly recognized to influence the risk of tumor development. Risk variants for colorectal cancer (CRC) have been mapped to chromosome positions 8q23.3, 8q24, 9p24.1, 10p14, 11q23, 14q22.2, 15q13, 16q22.1, 18q21, 19q13.1 and 20p12.3. In...
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