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Prognostic potential of whole exome sequencing in the clinical management of metachronous colorectal cancer liver metastases

26 Nov 2023

Abstract excerpt

BACKGROUND: Colorectal cancer is a highly prevalent and deadly. The most common metastatic site is the liver. We performed a whole exome sequencing analysis of a series of metachronous colorectal cancer liver metastases (mCLM) and matched non-malignant liver tissues to investigate the genomic profile of mCLM and explore associations with the patients' prognosis and therapeutic modalities. METHODS: DNA samples...

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PMID: 38008721
DOI: 10.1186/s12935-023-03135-x

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