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Article

Searching for candidate genes in familial BRCAX mutation carriers with prostate cancer.

Urologic oncology - 1 Mar 2016

Hunter Sally M, Rowley Simone M, Clouston David, Li Jason, Lupat Richard, Krishnananthan Nishanth, Risbridger Gail, Taylor Renea, Bolton Damien, Campbell Ian G, Thorne Heather

Abstract excerpt

OBJECTIVE: A family history of prostate cancer (PC) is a well-recognized high-risk factor for the development of clinically significant PC. To date, traditional linkage and association studies have identified only a limited number of genes and specific gene variants that account for only a small proportion of PC risk. To identify novel PC predisposition genes we performed whole-exome sequencing of PC-affected men...

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Source

Identifiers

PMID: 26585945
DOI: 10.1016/j.urolonc.2015.10.009

Genes

PARP2
ATRIP
BRCA1
BRCA2
DOK3
MCRS1
PCTP
PLEKHH3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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