Article
Screening for familial and hereditary prostate cancer.
International journal of cancer - 1 Jun 2016
Lynch Henry T, Kosoko-Lasaki Omofolasade, Leslie Stephen W, Rendell Marc, Shaw Trudy, Snyder Carrie, D'Amico Anthony V, Buxbaum Sarah, Isaacs William B, Loeb Stacy, Moul Judd W, Powell Isaac
Abstract excerpt
Prostate cancer (PC) has the highest degree of genetic transmission of any form of malignancy. In some families, the hereditary pattern is so strong as to mimic an autosomal dominance trait. We reviewed the known predisposing genetic markers to assess possible strategies for screening of families at risk. We carried out a systematic literature search using the Pubmed service of the National Center for...
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