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Article

Interleukin-17A genetic variants can confer resistance to brucellosis in Iranian population.

Cytokine - 1 Jan 2013

Rasouli Manoochehr, Asaei Sadaf, Kalani Mehdi, Kiany Simin, Moravej Ali

Abstract excerpt

On the subject of brucellosis, it seems that Th1/Th2 cytokines balance may be involved in the resistance or susceptibility to Brucella infection. In this respect, Th1 cytokines confer resistance, while Th2 cytokines predispose brucellosis. It is also clarified that IL-17 is required for the induction of IFN-γ and IL-12 in macrophages and dendritic cells. Then, it seems that IL-17 can affect the induction of Th1...

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Identifiers

PMID: 23131423
DOI: 10.1016/j.cyto.2012.10.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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