Article
Relationship between γ-interferon gene polymorphisms and susceptibility to brucellosis infection.
Microbiology and immunology - 1 Nov 2013
Eskandari-Nasab Ebrahim, Moghadampour Mehdi, Hasani Seyed-Shahaboddin, Hadadi-fishani Mehdi, Mirghanizadeh-Bafghi Seyyed-Ali, Asadi-Saghandi Abolghasem, Zare Fateme, Sadeghi-Kalani Behrooz, Ghazali-bina Mehran
Abstract excerpt
Interferon-gamma (IFN-γ) is a pro-inflammatory cytokine that plays a pivotal role in the defense mechanism against Brucella infection. It was hypothesized that the IFN-γ in (+874 A/T in intron 1) TT and +5644 T/A, TT genotypes, which are reportedly associated with high IFN production, are associa...
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