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Article

Polymorphisms and Plasma Levels of Tissue Inhibitor of Metalloproteinase-3: Impact on Genetic Susceptibility and Clinical Outcome of Oral Cancer.

Medicine - 1 Nov 2015

Su Chun-Wen, Huang Yi-Wen, Chen Mu-Kuan, Su Shih-Chi, Yang Shun-Fa, Lin Chiao-Wen

Abstract excerpt

Oral cancer, the fourth most common cancer among men in Taiwan, is associated with environmental carcinogens. Tissue inhibitor of metalloproteinase-3 (TIMP3), a member of the TIMP family, is the only protein that binds to the extracellular matrix for suppressing cancer cell growth, angiogenesis, migration, and invasion. The association of TIMP3 polymorphism with oral cancer susceptibility, however, has not yet...

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Source

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Identifiers

PMID: 26579821
DOI: 10.1097/MD.0000000000002092
PMCID: PMC4652830

Genes

TIMP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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