MMP-9 Genotypes Serve as Oral Cancer Predictive Marker for Smokers.

doi:10.21873/anticanres.18191

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MMP-9 Genotypes Serve as Oral Cancer Predictive Marker for Smokers.

Anticancer research - 1 Jun 2026

Shih Liang-Chun, Hsu Che-Lun, Yang Ya-Chen, Chen Jaw-Chyun, Chang Wen-Shin, Bau DA-Tian, Tsai Chia-Wen

Abstract excerpt

BACKGROUND/AIM: Oral cancer represents a major health burden in Taiwan, with tobacco use, alcohol consumption, and betel quid chewing recognized as predominant environmental risk factors. Matrix metalloproteinase-9 (MMP-9) has been implicated in tumor invasion and progression, and the promoter polymorphism rs3918242 has been investigated as a potential genetic determinant of cancer susceptibility. The study aims...

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PMID: 42203324
DOI: 10.21873/anticanres.18191

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