Article
TIMP-3 -1296 T>C and TIMP-4 -55 T>C gene polymorphisms play a role in the susceptibility of hepatocellular carcinoma among women.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Sept 2014
Tsai Hsiu-Ting, Hsieh Ming-Ju, Chiou Hui-Ling, Lee Hsiang-Lin, Hsin Min-Chieh, Liou Yi-Sheng, Yang Chen-Chieh, Yang Shun-Fa, Kuo Wu-Hsien
Abstract excerpt
The purpose of this study was to investigate genetic impact of TIMP-3 -1296 T>C (rs9619311) and TIMP-4 -55 T>C (rs3755724) gene polymorphisms on the susceptibility and clinicopathological characteristics of hepatocellular carcinoma (HCC). A total of 759 subjects, including 530 healthy controls and 229 patients with hepatocellular carcinoma, were recruited in this study. Allelic discrimination of TIMP-3 -1296 T>C...
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