Article
Protective Role of the Interleukin 33 rs3939286 Gene Polymorphism in the Development of Subclinical Atherosclerosis in Rheumatoid Arthritis Patients.
PloS one - 1 Jan 2015
López-Mejías Raquel, Genre Fernanda, Remuzgo-Martínez Sara, Robustillo-Villarino Montserrat, García-Bermúdez Mercedes, Llorca Javier, Corrales Alfonso, González-Juanatey Carlos, Ubilla Begoña, Miranda-Filloy José A, Mijares Verónica, Pina Trinitario, Blanco Ricardo, Alegre-Sancho Juan J, Ramírez Huaranga Marco A, Mínguez Sánchez María D, Tejera Segura Beatriz, Ferraz-Amaro Iván, Vicente Esther, Carmona F David, Castañeda Santos, Martín Javier, González-Gay Miguel A
Abstract excerpt
OBJECTIVES: To determine whether the interleukin-33 (IL-33)-interleukin-1 receptor like 1 (IL-1RL1) signaling pathway is implicated in the risk of subclinical atherosclerosis in patients with rheumatoid arthritis (RA). METHODS: A total of 576 Spanish RA patients from Northern Spain were genotyped for 6 well-known IL33-IL1RL1 polymorphisms (IL33 rs3939286, IL33 rs7025417, IL33 rs7044343, IL1RL1 rs2058660, IL1RL1...
