Article
Genetic variant in IL33 is associated with susceptibility to rheumatoid arthritis.
Arthritis research & therapy - 29 Apr 2014
Li Chun, Mu Rong, Guo Jianping, Wu Xinyu, Tu Xin, Liu Xu, Hu Fanlei, Guo Shiwei, Zhu Jiaxin, Xu Huji, Li Zhanguo
Abstract excerpt
INTRODUCTION: Interleukin (IL)-33 is a proinflammatory cytokine contributing to the pathogenesis of rheumatoid arthritis (RA). The gene encoding IL-33 may serve as a genetic factor and be associated with the risk of RA. To investigate the potential association between IL33 and RA, we performed a case-control study based on Chinese Han population. METHODS: A three-stage case-control study was performed. Two tag...
Topics
- Adult
- Aged
- Arthritis, Rheumatoid
- Asian People
- Case-Control Studies
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Interleukin-33
- Interleukins
- Male
- Middle Aged
- Polymorphism, Single Nucleotide