Influence of elevated-CRP level-related polymorphisms in non-rheumatic Caucasians on the risk of subclinical atherosclerosis and cardiovascular disease in rheumatoid arthritis.

doi:10.1038/srep31979

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Influence of elevated-CRP level-related polymorphisms in non-rheumatic Caucasians on the risk of subclinical atherosclerosis and cardiovascular disease in rheumatoid arthritis.

Scientific reports - 18 Aug 2016

López-Mejías Raquel, Genre Fernanda, Remuzgo-Martínez Sara, González-Juanatey Carlos, Robustillo-Villarino Montserrat, Llorca Javier, Corrales Alfonso, Vicente Esther, Miranda-Filloy José A, Magro César, Tejera-Segura Beatriz, Ramírez Huaranga Marco A, Pina Trinitario, Blanco Ricardo, Alegre-Sancho Juan J, Raya Enrique, Mijares Verónica, Ubilla Begoña, Mínguez Sánchez María D, Gómez-Vaquero Carmen, Balsa Alejandro, Pascual-Salcedo Dora, López-Longo Francisco J, Carreira Patricia, González-Álvaro Isidoro, Rodríguez-Rodríguez Luis, Fernández-Gutiérrez Benjamín, Ferraz-Amaro Iván, Castañeda Santos, Martín Javier, González-Gay Miguel A

Abstract excerpt

Association between elevated C-reactive protein (CRP) serum levels and subclinical atherosclerosis and cardiovascular (CV) events was described in rheumatoid arthritis (RA). CRP, HNF1A, LEPR, GCKR, NLRP3, IL1F10, PPP1R3B, ASCL1, HNF4A and SALL1 exert an influence on elevated CRP serum levels in non-rheumatic Caucasians. Consequently, we evaluated the potential role of these genes in the development of CV events...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged

Share to Arthritis, Rheumatoid

Share to Atherosclerosis

Share to C-Reactive Protein

Share to Cardiovascular Diseases

Share to Polymorphism, Genetic

Share to Risk Factors

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 27534721
DOI: 10.1038/srep31979
PMCID: PMC4989194

Genes

CRP
ASCL1
GCKR
LEPR
NLRP3
SALL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of elevated-CRP level-related polymorphisms in non-rheumatic Caucasians on the risk of subclinical atherosclerosis and cardiovascular disease in rheumatoid arthritis.PMID 27534721Read ↗

Influence of coronary artery disease and subclinical atherosclerosis related polymorphisms on the risk of atherosclerosis in rheumatoid arthritis.Semantic proximity Read ↗

Association of - 717 A > G (rs2794521) CRP polymorphism with high cardiovascular risk by C-reactive protein in systemic lupus erythematosus patients.Semantic proximity Read ↗

Lack of association between ABO, PPAP2B, ADAMST7, PIK3CG, and EDNRA and carotid intima-media thickness, carotid plaques, and cardiovascular disease in patients with rheumatoid arthritis.Semantic proximity Read ↗

Single-nucleotide polymorphisms at the 9p21.3 genomic region not associated with the risk of cardiovascular disease in patients with rheumatoid arthritis.Semantic proximity Read ↗

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.Semantic proximity Read ↗

Cardiovascular risk assessment in patients with rheumatoid arthritis: The relevance of clinical, genetic and serological markersSemantic proximity Read ↗

Polymorphism in the C-reactive protein (CRP) gene affects CRP levels in plasma and one early marker of atherosclerosis in men: The Health 2000 Survey.Semantic proximity Read ↗

Protective Role of the Interleukin 33 rs3939286 Gene Polymorphism in the Development of Subclinical Atherosclerosis in Rheumatoid Arthritis Patients.Semantic proximity Read ↗

Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels.Semantic proximity Read ↗

Lack of association between the CXCL12 rs501120 polymorphism and cardiovascular disease in Spanish patients with rheumatoid arthritis.Semantic proximity Read ↗

Association of the -757T>C polymorphism in the CRP gene with circulating C-reactive protein levels and carotid atherosclerosis.Semantic proximity Read ↗

Osteoprotegerin And MTHFR Gene Variations In Rheumatoid Arthritis: Association With Disease Susceptibility And Markers of Subclinical AtherosclerosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.