Article
The IL-33-ST2L pathway is associated with coronary artery disease in a Chinese Han population.
American journal of human genetics - 3 Oct 2013
Tu Xin, Nie Shaofang, Liao Yuhua, Zhang Hongsong, Fan Qian, Xu Chengqi, Bai Ying, Wang Fan, Ren Xiang, Tang Tingting, Xia Ni, Li Sisi, Huang Yuan, Liu Juan, Yang Qing, Zhao Yuanyuan, Lv Qiulun, Li Qingxian, Li Yue, Xia Yunlong, Qian Jin, Li Bin, Wu Gang, Wu Yanxia, Yang Yan, Wang Qing K, Cheng Xiang
Abstract excerpt
The effects of interleukin-33 (IL-33) on the immune system have been clearly demonstrated; however, in cardiovascular diseases, especially in coronary artery disease (CAD), these effects have not yet been clarified. In this study, we investigate the genetic role of the IL-33-ST2L pathway in CAD. We performed three-stage case-control association analyses on a total of 4,521 individuals with CAD and 4,809 controls...
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