Article
Phosphorylation Regulates Interaction of 210-kDa Myosin Light Chain Kinase N-terminal Domain with Actin Cytoskeleton.
Biochemistry. Biokhimiia - 1 Oct 2015
Vilitkevich E L, Khapchaev A Y, Kudryashov D S, Nikashin A V, Schavocky J P, Lukas T J, Watterson D M, Shirinsky V P
Abstract excerpt
High molecular weight myosin light chain kinase (MLCK210) is a multifunctional protein involved in myosin II activation and integration of cytoskeletal components in cells. MLCK210 possesses actin-binding regions both in the central part of the molecule and in its N-terminal tail domain. In HeLa cells, mitotic protein kinase Aurora B was suggested to phosphorylate MLCK210 N-terminal tail at serine residues...
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