Article
A role for gp210 in mitotic nuclear-envelope breakdown.
Journal of cell science - 1 Feb 2008
Galy Vincent, Antonin Wolfram, Jaedicke Andreas, Sachse Martin, Santarella Rachel, Haselmann Uta, Mattaj Iain
Abstract excerpt
The cytoplasmic and nuclear compartments of animal cells mix during mitosis on disassembly of the nuclear envelope (NE). NE breakdown (NEBD) involves the dispersion of the nuclear membranes and associated proteins, including nuclear pore complexes (NPCs) and the nuclear lamina. Among the approximately 30 NPC components known, few contain transmembrane domains. gp210 is a single-pass transmembrane glycoprotein of...
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