Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structure and function of polarity‐inducing kinase family MARK/Par‐1 within the branch of AMPK/Snf1‐related kinases

13 Jan 2010

Abstract excerpt

Kinases of the MARK/Par-1 family of S/T protein kinases are regulators of diverse cellular processes in Caenorhabditis elegans, Drosophila, yeast, and mammalian cells. They are involved in nematode embryogenesis, epithelial cell polarization, cell signaling, and neuronal differentiation. MARK phosphorylates microtubule-associated proteins such as tau and is a key regulator of microtubule-based intracellular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Metabolism, Diabetes, and Cancer
Share to Microtubule and mitosis dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20071654
DOI: 10.1096/fj.09-148064

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structure and function of polarity‐inducing kinase family MARK/Par‐1 within the branch of AMPK/Snf1‐related kinasesPMID 20071654Read ↗

Structure of the catalytic and ubiquitin-associated domains of the protein kinase MARK/Par-1.Semantic proximity Read ↗

PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila.Semantic proximity Read ↗

Microtubule affinity-regulating kinase 4: structure, function, and regulation.Semantic proximity Read ↗

Atypical PKC phosphorylates microtubule affinity-regulating kinase 4 in vitro.Semantic proximity Read ↗

AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation.Semantic proximity Read ↗

Mechanisms of Regulation and Diverse Activities of Tau-Tubulin Kinase (TTBK) IsoformsSemantic proximity Read ↗

A complex of MAST1 and 14-3-3η regulates Tau phosphorylation in the developing cortexSemantic proximity Read ↗

TTBK2: a tau protein kinase beyond tau phosphorylation.Semantic proximity Read ↗

A critical role for the PAR-1/MARK-tau axis in mediating the toxic effects of Aβ on synapses and dendritic spines.Semantic proximity Read ↗

MARK4 with an Alzheimer’s disease-related mutation promotes tau hyperphosphorylation directly and indirectly and exacerbates neurodegenerationSemantic proximity Read ↗

Multiprotein Assemblies, Phosphorylation and Dephosphorylation in Neuronal CytoskeletonSemantic proximity Read ↗

Role of phosphorylation in the mammalian circadian clock.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.