Article
Nature and Extent of Genetic Diversity of Dengue Viruses Determined by 454 Pyrosequencing.
PloS one - 1 Jan 2015
Choudhury Md Abu, Lott William B, Banu Shahera, Cheng Anthony Youzhi, Teo Yik-Ying, Ong Rick Twee-Hee, Aaskov John
Abstract excerpt
Dengue virus (DENV) populations are characteristically highly diverse. Regular lineage extinction and replacement is an important dynamic DENV feature, and most DENV lineage turnover events are associated with increased incidence of disease. The role of genetic diversity in DENV lineage extinctions is not understood. We investigated the nature and extent of genetic diversity in the envelope (E) gene of DENV...
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