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Article

The origin, emergence and evolutionary genetics of dengue virus.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 May 2003

Holmes Edward C, Twiddy S Susanna

Abstract excerpt

Dengue is one of the most important emerging viruses, posing a threat to one-third of the global human population. Herein we show how the comparative analysis of gene sequence data has shed light on the origin and spread of dengue virus, as well as on the evolutionary processes that structure its genetic diversity. This reveals that dengue virus has a relatively recent evolutionary history, with the four...

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Identifiers

PMID: 12797969
DOI: 10.1016/s1567-1348(03)00004-2

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